In recent years, many countries have liberalized the control of cannabis. Under the trend of legalization of cannabis, some products containing cannabis ingredients have also become daily consumer products, which have caused considerable impact on the sleeping pills market.
Does cannabis help sleep? In many impressions, marijuana is an exciting drug, but studies have shown that the component CBN (cannabinol) in cannabis has a certain sleeping and calming effect.
CBN is actually another by-product of cannabinoid THC (tetrahydrocannabinol) oxidation or degradation at high temperature, and THC is the hallucinogenic main chemical component in cannabis, the most important active substance in cannabis, with nerves Active, Lagunitas, a craft beer brand under Heineken, has launched soda containing THC.
A study by Steep Hill Labs, the first commercial cannabis laboratory in the United States , shows that CBN may be the most effective and effective sedative of cannabinoids. The sleep aid effect of 2.5mg-5mg CBN, and 5mg-10mg diazepam Treatment of anxiety insomnia) has the same effect.
However, the sleeping effect of CBN has not been fully confirmed. As early as the 1990s, researchers used mice to test eight CBN compounds. Only two of them can prolong the sleep cycle. CBN may also cause side effects such as loss of appetite, fatigue, and dizziness.
Dr. Shuhan He, a doctor at the Massachusetts Hospital, siad that CBN does have an effect on the sleep cycle, but whether it can be used as a sleep aid remains to be further studied.
Nevertheless, some marijuana producers have begun to introduce related products. In January of this year, California-based cannabis company Kiva Confections launched a soft candy containing 1mg CBN and 5mg THC, and used “help sleep” as a selling point.
Researchers at Kiva Confections found that the sleep-enhancing effect of CBN exceeded their expectations, so they decided to adjust the CBN content of the product to a low dose of 1 mg. Drew Ford, chief science officer at Kase Manufacturing, a cannabis laboratory in California, expects the market for CBN to grow rapidly in the next few years, and even to disrupt the healthcare industry.
Although there are not many cannabis drugs specifically used for sleeping, a study published by the American academic journal “Medical Supplement Therapy” last December showed that in areas where recreational marijuana is legalized, the number of patients who purchase over-the-counter sleeping pills has decreased significantly. The market share of sleeping pills dropped by 36%.
It shows that there is a clear negative correlation between the entry of recreational cannabis into the market and the sales of over-the-counter sleeping pills, suggesting that at least some recreational cannabis buyers use cannabis for therapeutic rather than recreational purposes.
This is a huge market, and insomnia is a worldwide problem. According to data from the World Health Organization , the insomnia rate of Chinese adults is close to 40%, and 300 million people have varying degrees of sleep disorders.
In addition to prescription sleeping pills, melatonin, an over-the-counter drug, is especially favored by insomniacs. In the United States, melatonin has annual sales of more than 400 million U.S. dollars . If CBN’s sleep-aid effect is further verified, it is likely to divide melatonin’s market share , Become the new “Sleep Medicine”.